Infection of guinea pigs with vesicular stomatitis New Jersey virus Transmitted by Culicoides sonorensis (Diptera: Ceratopogonidae).

Full Abstract

Intrathoracically inoculated Culicoides sonorensis Wirth & Jones were capable of transmitting vesicular stomatitis New Jersey virus (family Rhabdoviridae, genus Vesiculovirus, VSNJV) during blood feeding on the abdomen of six guinea pigs. None of the guinea pigs infected in this manner developed clinical signs of vesicular stomatitis despite seroconversion for VSNJV. Guinea pigs infected by intradermal inoculations of VSNJV in the abdomen also failed to develop clinical signs of vesicular stomatitis. Three guinea pigs given intradermal inoculations of VSNJV in the foot pad developed lesions typical of vesicular stomatitis. Transmission by the bite of C. sonorensis may have facilitated guinea pig infection with VSNJV because a single infected C. sonorensis caused seroconversion and all guinea pigs infected by insect bite seroconverted compared with 50% of the guinea pigs infected by intradermal inoculation with a higher titer VSNJV inoculum. The role of C. sonorensis in the transmission of VSNJV is discussed.

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Author information

Author/s: Pérez De León, Adalberto A (AA); O'Toole, Donal (D); Tabachnick, Walter J (WJ);

Affiliation: Arthropod-borne Animal Diseases Research Laboratory, USDA-ARS, P.O. Box 3965, Laramie, WY 82071-3965, USA.

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal: Journal of medical entomology (J Med Entomol), published in United States. (Language: eng)

Reference: 2006-May; vol 43 (issue 3) : pp 568-73

Dates: Created 2006/06/02; Completed 2006/06/23; Revised 2007/11/15;

PMID: 16739417, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Insect Vectors
Male
Rhabdoviridae Infections - transmission
Stomatitis - virology
Vesiculovirus - immunology

Associated Chemicals: Antibodies, Viral (0)

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