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| Research article summary (published 29 Jun 2006): |
A prospective study of risk factors for erectile dysfunction.
Full Abstract
PURPOSE:
We examined the impact of obesity, physical activity, alcohol use and smoking on the development of erectile dysfunction.
MATERIALS AND METHODS:
Subjects included 22,086 United States men 40 to 75 years old in the Health Professionals Followup Study cohort who were asked to rate their erectile function for multiple periods on a questionnaire mailed in 2000. Men who reported good or very good erectile function and no major chronic disease before 1986 were included in the analyses.
RESULTS:
Of men who were healthy and had good or very good erectile function before 1986, 17.7% reported incident erectile dysfunction during the 14-year followup. Obesity (multivariate relative risk 1.9, 95% CI 1.6-2.2 compared to men of ideal weight in 1986) and smoking (RR 1.5, 95% CI 1.3-1.7) in 1986 were associated with an increased risk of erectile dysfunction, while physical activity (RR 0.7, 95% CI 0.7-0.8 comparing highest to lowest quintile of physical activity) was associated with a decreased risk of erectile dysfunction. For men in whom prostate cancer developed during followup, smoking (RR 1.4, 95% CI 1.0-1.9) was the only lifestyle factor associated with erectile dysfunction.
CONCLUSIONS:
Reducing the risk of erectile dysfunction may be a useful and to this point unexploited motivation for men to engage in health promoting behaviors. We found that obesity and smoking were positively associated, and physical activity was inversely associated with the risk of erectile dysfunction developing.
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Author information
Author/s: Bacon, Constance G (CG); Mittleman, Murray A (MA); Kawachi, Ichiro (I); Giovannucci, Edward (E); Glasser, Dale B (DB); Rimm, Eric B (EB);
Affiliation: Department of Nutrition, Harvard School of Public Health, Channing Laboratory, 665 Huntington Avenue, Boston, MA 02115, USA.
Grants: CA 55075 (Agency:NCI NIH HHS) ; HL 35464 (Agency:NHLBI NIH HHS)
Journal and publication information
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal: The Journal of urology (J Urol), published in United States. (Language: eng)
Reference: 2006-Jul; vol 176 (issue 1) : pp 217-21
Dates: Created 2006/06/06; Completed 2006/07/27; Revised 2007/11/15;
PMID: 16753404, status: MEDLINE (last retrieval date: 12/26/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
Comments and Corrections
CommentIn: J Urol. 2006 Jul;176(1):10-1. (PMID: 16753355)
CommentIn: Nat Clin Pract Urol. 2007 Jan;4(1):16-7. (PMID: 17211418)
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