Toward single breath-hold whole-heart coverage coronary MRA using highly accelerated parallel imaging with a 32-channel MR system.

Full Abstract

Coronary MR angiography (CMRA) is generally confined to the acquisition of multiple targeted slabs with coverage dictated by the competing constraints of signal-to-noise ratio (SNR), physiological motion, and scan time. This work addresses these obstacles by demonstrating the technical feasibility of using a 32-channel coil array and receiver system for highly accelerated volumetric breath-hold CMRA. The use of the 32-element array in unaccelerated CMRA studies provided a baseline SNR increase of as much as 40% over conventional cardiac-optimized phased array coils, which resulted in substantially enhanced image quality and improved delineation of the coronary arteries. Modest accelerations were used to reduce breath-hold durations for tailored coverage of the coronary arteries using targeted multi-oblique slabs to as little as 10 s. Finally, high net accelerations were combined with the SNR advantages of a 3D steady-state free precession (SSFP) technique to achieve previously unattainable comprehensive volumetric coverage of the coronary arteries in a single breath-hold. The merits and limitations of this simplified volumetric imaging approach are discussed and its implications for coronary MRA are considered.Copyright (c) 2006 Wiley-Liss, Inc.

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Author information

Author/s: Niendorf, Thoralf (T); Hardy, Christopher J (CJ); Giaquinto, Randy O (RO); Gross, Patrick (P); Cline, Harvey E (HE); Zhu, Yudong (Y); Kenwood, Gontran (G); Cohen, Shmuel (S); Grant, Aaron K (AK); Joshi, Sanjay (S); Rofsky, Neil M (NM); Sodickson, Daniel K (DK);

Affiliation: Applied Science Laboratory, GE Healthcare Technologies, Boston, Massachusetts, USA. niendorf(-atsign-)rad.rwth-aachen.de

Journal and publication information

Publication Type: Journal Article

Journal: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine (Magn Reson Med), published in United States. (Language: eng)

Reference: 2006-Jul; vol 56 (issue 1) : pp 167-76

Dates: Created 2006/06/28; Completed 2006/11/13;

PMID: 16755538, status: MEDLINE (last retrieval date: 12/26/2008)

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Coronary Angiography - methods
Coronary Vessels
Heart - radiography
Humans

Image Processing, Computer-Assisted
Magnetic Resonance Angiography - methods
Phantoms, Imaging
Respiration

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