Research article summary (published 13 May 2006):

[Pain and depression]

(Smerter og depression.)

Full Abstract

Pain and depression are often associated. The frequency of pain complaints in depressed patients is 13-100%. In general, depressed patients have a higher pain threshold than do controls, but lower and unchanged thresholds have also been observed. The frequency of depression in chronic pain patients is 1.5-100%. Pain etiology, short education, marital status, gender, psychiatric family history and unemployment are risk factors for depression. Possible mechanisms underlying the pathophysiology of depression and pain could be involvement of the monoamines (5-HT and NA) and the HPA axis.

Author information

Author/s: Gormsen, Lise (L); Jensen, Troels Staehelin (TS); Bach, Flemming Winther (FW); Rosenberg, Raben (R);

Affiliation: Arhus Sygehus, Dansk Smerteforskningscenter, og Psykiatrisk Hospital i Arhus, Arhus C. lise.gormsen(-atsign-)ki.au.dk

Journal and publication information

Publication Type: English Abstract; Journal Article; Review

Journal: Ugeskrift for laeger (Ugeskr Laeger), published in Denmark. (Language: dan)

Reference: 2006-May; vol 168 (issue 20) : pp 1967-9

Dates: Created 2006/06/13; Completed 2006/06/21; Revised 2006/11/15;

PMID: 16768896, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Central Nervous System - metabolism Chronic Disease Depression - complications Female Humans Male

Nociceptors - metabolism; physiology Norepinephrine - metabolism Pain - etiology; psychology Pain Threshold - physiology Risk Factors Serotonin - metabolism

Associated Chemicals: Serotonin (50-67-9) ; Norepinephrine (51-41-2)

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