Taste aversion in rats induced by forced swimming, voluntary running, forced running, and lithium chloride injection treatments.

Full Abstract

The present experiment compared the strengths of taste aversion learning in rats induced by forced swimming in a water pool (5, 15, 30, or 60 min), voluntary running in an activity wheel (15, 30, 60, or 120 min), forced running in a motorized wheel (60 min at the speed of 8 m/min), optional running in the apparatus consisting of an activity wheel and a side room (120 min), and a lithium chloride (LiCl, 0.15 M LiCl at 2% of body weight) injection. The rats were given an access to saccharin solution immediately followed by one of the above treatments or simply returned back to the home cages for the control group. On the next 2 days, aversion to the saccharin solution was assessed by two-bottle choice testing between it and tap water. The following results were obtained. (1) The saccharin aversion was a positive function of exercise durations in the forced swimming and voluntary running rats, and the exercise of more than 30 min induced statistically significant saccharin aversion, compared with the control rats. (2) The forced running caused relatively strong saccharin aversion. The group of forced running rats acquired the numerically strongest saccharin aversion on average among all exercised rats. (3) The optional running treatment had little effect. (4) The LiCl injection resulted in the strongest aversion among the all treatments explored here.

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Author information

Author/s: Masaki, Takahisa (T); Nakajima, Sadahiko (S);

Affiliation: Psychology Section, Department of Integrated Psychological Science, Kwansei Gakuin University, Nishinomiya, Hyogo 662-8501, Japan. masakit(-atsign-)kwansei.ac.jp

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal: Physiology & behavior (Physiol Behav), published in United States. (Language: eng)

Reference: 2006-Jul; vol 88 (issue 4-5) : pp 411-6

Dates: Created 2006/07/31; Completed 2006/09/28; Revised 2006/11/15;

PMID: 16777150, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Animals
Avoidance Learning - drug effects
Lithium Chloride - pharmacology
Male
Rats

Rats
Rats, Wistar
Running - physiology
Swimming - physiology
Taste - drug effects

Associated Chemicals: Lithium Chloride (7447-41-8)

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