Low-grade gliomas in adults.

Full Abstract

Low-grade gliomas are a heterogeneous group of neoplasms usually encountered in younger patient populations. These tumors represent a unique challenge because most patients will survive a decade or more and may be at a higher risk for treatment-related complications. Clinical observations over the years have identified a subset of low-grade gliomas that tends to manifest more aggressive clinical behavior and require earlier, more aggressive intervention. Clinical and molecular parameters may allow better assessment of prognosis and application of risk-adjusted management strategies that may include resection, radiation, or chemotherapy. Improved methods of long-term cognitive and functional assessment are desperately needed in this patient population.

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Author information

Author/s: Grier, Jeanine T (JT); Batchelor, Tracy (T);

Affiliation: Division of Neuro-Oncology, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Journal and publication information

Publication Type: Journal Article; Review

Journal: The oncologist (Oncologist), published in United States. (Language: eng)

Reference: 2006-Jun; vol 11 (issue 6) : pp 681-93

Dates: Created 2006/06/23; Completed 2006/12/07;

PMID: 16794247, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Brain Neoplasms - diagnosis; pathology; therapy
Glioma - diagnosis; pathology; therapy

Humans
Prognosis

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