Nicotine replacement therapy: patterns of use after a quit attempt among methadone-maintained smokers.

Full Abstract

AIM:
To determine the association between daily smoking and use of nicotine replacement therapy (NRT), and to determine predictors of greater NRT use among methadone-maintained smokers.

INTERVENTION:
Assignment to free nicotine patch (8 to 12 weeks) plus either (1) a baseline-tailored brief motivational intervention, a quit date behavioral skills counseling session, and a relapse prevention follow-up session (max), or (2) brief advice using NCI's 4 A's model (min).

SETTING:
Five methadone maintenance treatment centers.

PARTICIPANTS:
Of the 383 methadone-maintained smokers enrolled, 309 (80.6%) set a specific quit date (received NRT) and were located for assessments. Participants were 51.8% male, 78.6% Caucasian, and smoked 26.6 (SD=12.2) cigarettes/day.

OUTCOME:
Use of NRT and smoking behaviors during the 180-day follow-up period assessed by the Timeline follow-back method.

FINDINGS:
On the day following their quit day, 86.4% of participants used NRT. The percentage of participants using NRT was 52.3%, 27.1%, and 10.4% on day 30, day 60, and day 90, respectively. Participants used NRT on 44.1% of the days through the 90 days of the treatment protocol. The estimated odds of smoking abstinence was 7.1 (P<.001) times higher on days when NRT was used than on days when NRT was not used, and cigarettes/day was also significantly lower on NRT days (14.93 vs 4.65; P<.001).

CONCLUSION:
Nicotine replacement therapy use was inconsistent following an initial quit attempt among methadone-maintained smokers. On days when NRT was used, individuals were likely to smoke at reduced levels or not at all.

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Author information

Author/s: Stein, Michael D (MD); Anderson, Bradley J (BJ); Niaura, Raymond (R);

Affiliation: Department of Medicine, Brown Medical School, Providence, RI, USA. mstein(-atsign-)life-span.org

Grants: K24 DA00512 (Agency:NIDA NIH HHS) ; R01 CA84392 (Agency:NCI NIH HHS)

Journal and publication information

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural

Journal: Journal of general internal medicine : official journal of the Society for Research and Education in Primary Care Internal Medicine (J Gen Intern Med), published in United States. (Language: eng)

Reference: 2006-Jul; vol 21 (issue 7) : pp 753-7

Dates: Created 2006/06/30; Completed 2006/09/12; Revised 2008/11/20;

PMID: 16808777, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Administration, Topical
Adult
Female
Follow-Up Studies
Humans
Male
Methadone - therapeutic use

Methadone - therapeutic use
Middle Aged
Nicotine - administration & dosage; therapeutic use
Randomized Controlled Trials as Topic
Smoking
Smoking Cessation - methods
Treatment Outcome

Associated Chemicals: Nicotine (54-11-5) ; Methadone (76-99-3)

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