Research article summary (published 30 Dec 2004):

Surgical treatment options in young women with breast cancer.

Full Abstract

The diagnosis of breast cancer in young women presents particular challenges in surgical decision making and treatment. These challenges arise from concurrent genetic or other risk factors, potentially more aggressive tumor biology, larger tumor size, and psychosocial factors unique to young women. Local recurrence and survival rates for breast-conserving surgery compared to mastectomy are reviewed and strategies for reducing local recurrence after breast conserving therapy are discussed. Options for incorporating genetic testing and counseling into surgical management are presented. Management of young women with BRCA gene mutations, with a positive family history without a risk gene mutation, and with a history of mantle irradiation for Hodgkin's disease is discussed.

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Author information

Author/s: Black, Dalliah (D); Smith, Barbara L (BL);

Affiliation: Division of Surgical Oncology, Massachusetts General Hospital, Boston, 02114, USA.

Journal and publication information

Publication Type: Journal Article; Review

Journal: Breast disease (Breast Dis), published in Netherlands. (Language: eng)

Reference: -2005-2006; vol 23 (issue ) : pp 37-45

Dates: Created 2006/07/06; Completed 2006/08/31;

PMID: 16823165, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adult Biopsy Breast - pathology Breast Neoplasms - genetics; pathology; surgery Decision Making Female

Female Genes, BRCA1 Genes, BRCA2 Humans Mutation Neoplasm Recurrence, Local

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