The mismatch negativity in cognitive and clinical neuroscience: theoretical and methodological considerations.

Full Abstract

Mismatch negativity (MMN) component of the event-related brain potentials has become popular in cognitive and clinical brain research during the recent years. It is an early response to a violation of an auditory rule such as an infrequent change in the physical feature of a repetitive sound. There is a lot of evidence on the association of the MMN parameters and behavioral discrimination ability, although this relationship is not always straight-forward. Since the MMN reflects sound discrimination accuracy, it can be used for probing how well different groups of individuals perceive sound differences, and how training or remediation affects this ability. In the present review, we first introduce some of the essential MMN findings in probing sound discrimination, memory, and their deficits. Thereafter, issues which need to be taken into account in MMN investigations as well as new improved recording paradigms are discussed.

Author information

Author/s: Kujala, Teija (T); Tervaniemi, Mari (M); Schröger, Erich (E);

Affiliation: Helsinki Collegium for Advanced Studies, University of Helsinki, FIN-00014 Helsinki, Finland. teija.m.kujala(-atsign-)helsinki.fi

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal: Biological psychology (Biol Psychol), published in Netherlands. (Language: eng)

Reference: 2007-Jan; vol 74 (issue 1) : pp 1-19

Dates: Created 2006/11/27; Completed 2007/03/13;

PMID: 16844278, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article
(including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.