Chemoprevention of prostate cancer.

Full Abstract

Prostate cancer is a common malignancy with multiple potential opportunities for cancer prevention. As the genetic basis of this malignancy is further understood, prevention strategies will be developed for individual patients based on specific risk factors and pathways of carcinogenesis. The PCPT has conclusively proven that prostate cancer prevention is possible. The results of the SELECT should be available within several years. An enormous challenge for the medical community will be the development of an efficient strategy to evaluate the substantial number of dietary, behavioral, and pharmacologic prevention opportunities. Ultimately, the goal of prostate can-cer prevention is to (1) identify men who are destined to develop clinically significant prostate cancer, and (2) provide individualized agents to prevent disease development.

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Author information

Author/s: Brand, Timothy C (TC); Canby-Hagino, Edith D (ED); Pratap Kumar, A (A); Ghosh, Rita (R); Leach, Robin J (RJ); Thompson, Ian M (IM);

Affiliation: University of Texas Health Science Center, San Antonio, TX 78229, USA.

Journal and publication information

Publication Type: Journal Article; Review

Journal: Hematology/oncology clinics of North America (Hematol Oncol Clin North Am), published in United States. (Language: eng)

Reference: 2006-Aug; vol 20 (issue 4) : pp 831-43

Dates: Created 2006/07/24; Completed 2006/10/11;

PMID: 16861117, status: MEDLINE (last retrieval date: 12/26/2008)

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Anticarcinogenic Agents - therapeutic use
Chemoprevention - methods
Humans
Male

Male
Prostatic Neoplasms - prevention & control
Risk Assessment
Treatment Outcome

Associated Chemicals: Anticarcinogenic Agents (0)

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