Research article summary (published 23 Jul 2006):

Identification of subgroups in amnestic mild cognitive impairment.

Full Abstract

The DMS48 is a visual recognition memory test designed to detect memory changes in early Alzheimer disease (AD). Patients with amnestic mild cognitive impairment (aMCI) who succeeded on this task exhibited frontal hypoperfusion on SPECT. In contrast, failure was associated with temporomesial and temporoparietal hypoperfusion, a pattern usually described in the early stages of AD. It may possible to detect patients at high risk for AD within a population of aMCI.

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Author information

Author/s: Guedj, E (E); Barbeau, E J (EJ); Didic, M (M); Felician, O (O); de Laforte, C (C); Ceccaldi, M (M); Mundler, O (O); Poncet, M (M);

Affiliation: Service Central de Biophysique et de Médecine Nucléaire, Assistance Publique des Hôpitaux de Marseille, Centre Hospitalo-Universitaire de la Timone, Marseille, France. eric.guedj(-atsign-)ap-hm.fr

Journal and publication information

Publication Type: Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

Journal: Neurology (Neurology), published in United States. (Language: eng)

Reference: 2006-Jul; vol 67 (issue 2) : pp 356-8

Dates: Created 2006/07/25; Completed 2006/08/14; Revised 2006/11/15;

PMID: 16864841, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Aged Aged, 80 and over Amnesia - classification; complications; diagnosis Cognition Disorders - classification; complications; diagnosis Female Humans

Male Middle Aged Neuropsychological Tests Reproducibility of Results Sensitivity and Specificity Severity of Illness Index

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