Use of genome browsers to locate your favorite genes.

Full Abstract

The completion of whole-genome sequencing projects offers the opportunity of creating high-resolution maps of specific segments in a known genomic DNA sequence. For this purpose, several genome browsers have been created. They include the map-view (http://www.ncbi.nlm.nih.gov/mapview/), the Ensembl genome browser (http://www.ensembl.org/), and the genome browser at UCSC (http://genome.ucsc.edu/). For the beginners in the field, through a specific example, this chapter provides a step-by-step procedure for creating a map using the genome browser at UCSC. The example describes mapping, in the human genome, the promoter region of the NF-IL6 gene. The procedure is applicable to creating maps of the desired regions in genomes of other species available at the genome browser at UCSC.

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Author information

Author/s: Bina, Minou (M);

Affiliation: Department of Chemistry, Purdue University, West Lafayette, IN, USA.

Journal and publication information

Publication Type: Journal Article

Journal: Methods in molecular biology (Clifton, N.J.) (Methods Mol Biol), published in United States. (Language: eng)

Reference: 2006-; vol 338 (issue ) : pp 1-7

Dates: Created 2006/08/04; Completed 2006/09/28;

PMID: 16888346, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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