Research article summary (published 30 Jul 2006):

Perirhinal cortex lesions impair simultaneous but not serial feature-positive discrimination learning.

Full Abstract

The role of the perirhinal cortex in discriminative eyeblink conditioning was examined by means of feature-positive discrimination procedures with simultaneous (A-/XA+) and serial (A-/X-->A+) stimulus compounds. Lesions of the perirhinal cortex severely impaired acquisition of simultaneous feature-positive discrimination but produced no impairment in serial feature-positive discrimination. The results suggest that the perirhinal cortex plays a role in discriminative eyeblink conditioning by resolving ambiguity in discriminations with overlapping stimulus elements.

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Author information

Author/s: Campolattaro, Matthew M (MM); Freeman, John H (JH);

Affiliation: Department of Psychology, University of Iowa, Iowa City, IA 52242, USA.

Grants: R01 MH065483-05 (Agency:NIMH NIH HHS)

Journal and publication information

Publication Type: Comparative Study; Journal Article

Journal: Behavioral neuroscience (Behav Neurosci), published in United States. (Language: eng)

Reference: 2006-Aug; vol 120 (issue 4) : pp 970-5

Dates: Created 2006/08/08; Completed 2006/09/28; Revised 2008/11/20;

PMID: 16893302, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Animals Brain Injuries - complications Conditioning (Psychology) - physiology Discrimination Learning - physiology Entorhinal Cortex - pathology; physiopathology

Learning Disorders - etiology; pathology Male Rats Rats, Long-Evans Serial Learning - physiology

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