Ocular pulse amplitude in healthy subjects as measured by dynamic contour tonometry.

Full Abstract

OBJECTIVES:
To test whether dynamic contour tonometry yields ocular pulse amplitude (OPA) measurements that are independent of corneal thickness and curvature, and to assess variables of observer agreement.

METHODS:
In a multivariate cluster analysis on 223 eyes, the relationship between central corneal thickness, corneal curvature, axial length, anterior chamber depth, intraocular pressure, sex, age, and OPA measurements was assessed. Intraobserver and interobserver variabilities were calculated from repeated measurements obtained from 8 volunteers by 4 observers.

RESULTS:
The OPA readings were not affected by central corneal thickness (P = .08), corneal curvature (P = .47), anterior chamber depth (P = .80), age (P = .60), or sex (P = .73). There was a positive correlation between OPA and intraocular pressure (0.12 mm Hg/1 mm Hg of intraocular pressure; P<.001) and a negative correlation between OPA and axial length (0.27 mm Hg/1 mm of length; P<.001). Intraobserver and interobserver variabilities were 0.08 and 0.02 mm Hg, respectively, and the intraclass correlation coefficient was 0.89.

CONCLUSIONS:
The OPA readings obtained with dynamic contour tonometry in healthy subjects are not influenced by the structure of the anterior segment of the eye but are affected by intraocular pressure and axial length. We found a high amount of agreement within and between observers.

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Author information

Author/s: Kaufmann, Claude (C); Bachmann, Lucas M (LM); Robert, Yves C (YC); Thiel, Michael A (MA);

Affiliation: Department of Ophthalmology and Horten Centre for Patient Oriented Research, University of Zürich, Zürich, Switzerland.

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal: Archives of ophthalmology (Arch Ophthalmol), published in United States. (Language: eng)

Reference: 2006-Aug; vol 124 (issue 8) : pp 1104-8

Dates: Created 2006/08/15; Completed 2006/08/28; Revised 2006/11/15;

PMID: 16908812, status: MEDLINE (last retrieval date: 12/26/2008)

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adult
Anterior Chamber - anatomy & histology
Anthropometry
Cornea - anatomy & histology
Eye - anatomy & histology
Female
Humans

Humans
Intraocular Pressure - physiology
Male
Middle Aged
Multivariate Analysis
Observer Variation
Tonometry, Ocular - instrumentation; methods

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