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| Research article summary (published 29 Sep 2006): |
Neuropharmacological evaluation of Ginkgo biloba phytosomes in rodents.
Full Abstract
On oral administration, Ginkgo biloba phytosomes significantly reduced pentobarbitone-induced sleeping time, produced an alteration in the general behaviour pattern, increased spontaneous motility and inhibited the chlorpromazine-induced blockade of conditioned and unconditioned responses in rodents. They exhibited both antiamnestic and antidepressant activities in the scopolamine-induced amnesia test and behavioural despair test, respectively. However, the phytosomes failed to show anticonvulsant activity. The observations suggest that the G. biloba phytosomes possess moderate antiamnestic/nootropic activity.Copyright 2006 John Wiley & Sons, Ltd.
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Author information
Author/s: Naik, Suresh R (SR); Pilgaonkar, Vinaya W (VW); Panda, Vandana S (VS);
Affiliation: Department of Pharmacology and Toxicology, Principal K. M. Kundnani College of Pharmacy, Jote Joy Building, Rambhau Salgaonkar Marg, Cuffe Parade, Colaba, Mumbai 400 005, India. srnaik5(-atsign-)rediffmail.com
Journal and publication information
Publication Type: Journal Article
Journal: Phytotherapy research : PTR (Phytother Res), published in England. (Language: eng)
Reference: 2006-Oct; vol 20 (issue 10) : pp 901-5
Dates: Created 2006/09/27; Completed 2007/01/03;
PMID: 16909444, status: MEDLINE (last retrieval date: 12/26/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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