Clinical and epidemiologic studies of nonsyndromic cleft lip and palate in china: analysis of 4268 cases.

Full Abstract

The aim of our study was to review clinical and epidemiologic characteristic of the nonsyndromic cleft lip and cleft palate over a period of 10 years at West China Stomatological Hospital, Sichuan University. Four thousand two hundred sixty-eight nonsyndromic cleft lip and cleft palate cases were retrospectively analyzed according to the following variables:
general information, cleft type, maternal age, familial history, as well as associated malformations, et al. In these cases, 1075 of which were cleft lip, 1985 were cleft lip with cleft palate; 1208 were isolated cleft palate. There were more men than women in the cleft lip and cleft lip with cleft palate group, while there were more women than men in the isolated cleft palate group. There were significantly more unilateral cleft lip cases than cleft lip on both sides; the cases of cleft lip on the left side were more than that of cleft lip on the right side. The cases with inherited history accounted for 6.68% of all the cases. Most infection cases occurred among the deleterious factors and the complications experienced during the first 3 months after the pregnancy. In all of the 14 twin cases, only 1 of the babies was affected. There were totally 152 cases with other associated malformations. Patients with cleft lip born in November to January were less than those born in the other three quarters of the year. Patients of A blood group composed a higher proportion than the control group. Our data may provide references for appropriate resource use, cleft lip and cleft palate prevention programs, and counseling programs with China-specific data.

Learn Faster Today Improve your study skills

Author information

Author/s: Meng, Tian (T); Shi, Bing (B); Zheng, Qian (Q); Wang, Yan (Y); Li, Sheng (S);

Affiliation: Department of Oral and Maxillofacial Surgery, West China College of Stomatology, Sichuan University, Chengdu, People's Republic of China.

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal: Annals of plastic surgery (Ann Plast Surg), published in United States. (Language: eng)

Reference: 2006-Sep; vol 57 (issue 3) : pp 264-9

Dates: Created 2006/08/24; Completed 2007/02/27;

PMID: 16929191, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article (including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.

MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adult
China
Cleft Lip - diagnosis; epidemiology
Cleft Palate - diagnosis; epidemiology
Female

These are the highest related articles currently in the database:

Treatment of oralfacial clefts by state-affiliated craniofacial centers and cleft palate clinics. 30 Aug 2003
Factors determining occurrence of cleft lip and cleft palate. 30 Dec 1977
Assessment of the patient with cleft lip and palate. A developmental approach. 29 Sep 1993
Cleft lip and palate: the Jos experience. 29 Sep 2002
[Cheilognathouranoschisis (author's transl)] 31 Mar 1974
The incidence of cleft lip and palate in Nigeria. 29 Jun 1982
Facial clefts among epileptic patients. 30 Mar 1981
Studies of cleft lip and cleft palate in east European populations. 30 Dec 1979
The incidence, classification, etiology, and embryology of oral clefts. 30 Aug 1996
[Cheilognathopalatoschisis: its embryology, epidemiology, etiology, clinical picture and therapy. The experience of a division of pediatrics] 29 Jun 1998

See 100+ related articles.