Allergy-preventive phenolic glycosides from Populus sieboldii.

Full Abstract

Allergy-preventive activity was demonstrated for an extract of the bark of Populus sieboldii in a continuing search for allergy-preventive substances from natural sources. By bioassay-directed fractionation of this plant bark, two new phenolic glycosides, siebolside A {2-hydroxy-5-[(benzoyloxy)methyl]phenyl (6'-O-acetyl) beta-D-glucopyranoside} (1) and siebolside B {2-hydroxy-5-[(benzoyloxy)methyl]phenyl beta-D-glucopyranoside} (2), were isolated, together with three known compounds, salicin (3), sakuranin (4), and neosakuranin (5). The structures of 1 and 2 were elucidated by spectroscopic methods. Compounds 1-5 all showed allergy-preventive effects.

Learn Faster Today Improve your study skills

Author information

Author/s: Ogawa, Yuko (Y); Oku, Hisae (H); Iwaoka, Emiko (E); Iinuma, Munekazu (M); Ishiguro, Kyoko (K);

Affiliation: School of Pharmaceutical Sciences, Mukogawa Women's University, Koshien Kyuban-cho, Nishinomiya, 663-8179, Japan.

Journal and publication information

Publication Type: Journal Article

Journal: Journal of natural products (J Nat Prod), published in United States. (Language: eng)

Reference: 2006-Aug; vol 69 (issue 8) : pp 1215-7

Dates: Created 2006/08/28; Completed 2006/09/28;

PMID: 16933880, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article (including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.

MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Animals
Blood Platelets - drug effects
Glucosides
Glycosides - blood; chemistry; isolation & purification; pharmacology
Hypersensitivity - prevention & control
Japan

Japan
Mice
Molecular Structure
Phenols - blood; chemistry; isolation & purification; pharmacology
Plant Bark - chemistry
Populus - chemistry

Associated Chemicals: Glucosides (0) ; Glycosides (0) ; Phenols (0) ; siebolside A (0) ; siebolside B (0)

These are the highest related articles currently in the database:

See 100+ related articles.