[Neuropsychological markers for the diagnosis of Alzheimer's disease]

(Les marqueurs neuropsychologiques du diagnostic de la maladie d'Alzheimer.)

Full Abstract

Better knowledge of the preclinical phase of Alzheimer's disease and of the symptomatic pre-dementia stage designated "mild cognitive impairment" will require considerable progress in our understanding of neuropsychological processes. The results of studies suggest that impaired performance in memory tests may serve as a marker for Alzheimer's disease. The best current predictors include stringent tests of episodic memory and recognition tests. The early stages of Alzheimer's disease also seem to involve subtle deficits in semantic memory and attentional processes. Face recognition and denomination seem to be useful tools. Greater accuracy and precision in the transitional zone between healthy aging and the first manifestations of Alzheimer's disease will require work combining data on neuropsychological profiles and neuroimaging.

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Author information

Author/s: Thomas-Anterion, C (C); Laurent, B (B);

Affiliation: Unité de Neuropsychologie, CM2R, CHU Bellevue, 42055 Saint-Etienne cedex 05, France. catherine.thomas(-atsign-)chu-st-etienne.fr

Journal and publication information

Publication Type: English Abstract; Journal Article; Review

Journal: Revue neurologique (Rev Neurol (Paris)), published in France. (Language: fre)

Reference: 2006-Oct; vol 162 (issue 10) : pp 913-20

Dates: Created 2006/10/09; Completed 2006/11/14; Revised 2006/11/15;

PMID: 17028558, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Aged
Alzheimer Disease - diagnosis; pathology; physiopathology; psychology
Biological Markers - analysis
Cognition Disorders

Associated Chemicals: Biological Markers (0)

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