AUTO3DEM--an automated and high throughput program for image reconstruction of icosahedral particles.

Full Abstract

AUTO3DEM is an automation system designed to accelerate the computationally intensive process of three-dimensional structure determination from images of vitrified icosahedral virus particles. With minimal user input and intervention, AUTO3DEM manages the flow of data between the major image reconstruction programs, monitors the progress of the computations, and intelligently updates the input parameters as the resolution of the model is improved. It is designed to be used on any computer running the Linux or UNIX operating systems and can be run in parallel mode on multi-processor systems.

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Author information

Author/s: Yan, Xiaodong (X); Sinkovits, Robert S (RS); Baker, Timothy S (TS);

Affiliation: Department of Chemistry & Biochemistry, University of California, San Diego, La Jolla, CA 92093-0378, USA. xyan(-atsign-)ucsd.edu

Grants: P01 AI055672-03 (Agency:NIAID NIH HHS) ; R01 AI-055672 (Agency:NIAID NIH HHS) ; R37 GM033050-23 (Agency:NIGMS NIH HHS) ; R37 GM033050-24 (Agency:NIGMS NIH HHS) ; R37GM-033050 (Agency:NIGMS NIH HHS)

Journal and publication information

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal: Journal of structural biology (J Struct Biol), published in United States. (Language: eng)

Reference: 2007-Jan; vol 157 (issue 1) : pp 73-82

Dates: Created 2006/12/15; Completed 2007/03/21; Revised 2008/11/20;

PMID: 17029842, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Algorithms
Automatic Data Processing
Image Processing, Computer-Assisted - methods

Image Processing, Computer-Assisted - methods
Software
Viruses - chemistry

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