[Medical treatment of Alzheimer's disease]

(Medicinsk behandling af Alzheimers sygdom.)

Full Abstract

In Denmark, Alzheimer drugs have been registered since 1997. Three cholinesterase inhibitors (donepezil, rivastigmin og galantamin) are approved mild to moderate Alzheimer's disease and one partial NMDA receptor antagonist (memantin) with the indication moderate to severe Alzheimer's disease. The treatment is symptomatic with a parallel shift of the course. The life expectancy does not seem to be altered. There is documented effect on the cholinesterase inhibitors of up to two years and for memantine for 6 months. New disease modifying agents are under clinical development.

Author information

Author/s: Johannsen, Peter (P);

Affiliation: H:S Hukommelsesklinikken, Neurologisk Klinik, H:S Rigshospitalet, København Ø. peterj(-atsign-)dadlnet.dk

Journal and publication information

Publication Type: English Abstract; Journal Article; Review

Journal: Ugeskrift for laeger (Ugeskr Laeger), published in Denmark. (Language: dan)

Reference: 2006-Oct; vol 168 (issue 40) : pp 3424-9

Dates: Created 2006/10/11; Completed 2006/10/17; Revised 2007/11/15;

PMID: 17032609, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

Comments and Corrections

CommentIn: Ugeskr Laeger. 2006 Oct 30;168(44):3833; author reply 3833. (PMID: 17131519)

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Associated Chemicals: Cholinesterase Inhibitors (0) ; Indans (0) ; Nootropic Agents (0) ; Phenylcarbamates (0) ; Piperidines (0) ; donepezil (120011-70-3) ; rivastigmine (123441-03-2) ; Memantine (19982-08-2) ; Galantamine (357-70-0)

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