[Psychopharmacological treatment of behavioral and psychological symptoms in dementia]

(Psykofarmakologisk behandling af psykiatriske symptomer og adfaerdsforstyrrelser ved demens.)

Full Abstract

Behavioural and psychological symptoms of dementia (BPSD) are common and can dominate disease presentation. Antidepressions are commonly prescribed for depressive symptoms, but the evidence to support this practice is weak. The atypical antipsychotics risperidone and olanzepine have significant efficacy for the treatment of aggression and risperidone is also efficacious in the treatment of psychosis, but both with substantially increased risk of stroke. There are no newer studies of benzodiazepines in the treatment of anxiety and in old studies the efficacy are doubtful.

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Author information

Author/s: Lolk, Annette (A); Gulmann, Niels Christian (NC);

Affiliation: Syddansk Universitet, Klinisk Institut, Forskningsenheden for Psykiatri, Psykiatrisk Afdeling P, Odense C. annette.lolk(-atsign-)ouh.fyns-amt.dk

Journal and publication information

Publication Type: English Abstract; Journal Article; Review

Journal: Ugeskrift for laeger (Ugeskr Laeger), published in Denmark. (Language: dan)

Reference: 2006-Oct; vol 168 (issue 40) : pp 3429-32

Dates: Created 2006/10/11; Completed 2006/10/17; Revised 2008/11/21;

PMID: 17032610, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Anti-Anxiety Agents - adverse effects; therapeutic use
Anticonvulsants - adverse effects; therapeutic use
Antidepressive Agents - adverse effects; therapeutic use
Antipsychotic Agents - adverse effects; therapeutic use
Benzodiazepines - adverse effects; therapeutic use
Dementia - complications; drug therapy; psychology

Dementia - complications; drug therapy; psychology
Humans
Mental Disorders - complications; drug therapy
Risperidone - adverse effects; therapeutic use
Serotonin Uptake Inhibitors - adverse effects; therapeutic use
Treatment Outcome

Associated Chemicals: Anti-Anxiety Agents (0) ; Anticonvulsants (0) ; Antidepressive Agents (0) ; Antipsychotic Agents (0) ; Serotonin Uptake Inhibitors (0) ; Risperidone (106266-06-2) ; Benzodiazepines (12794-10-4) ; olanzapine (132539-06-1)

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