Lifetime prevalence and inter-cohort variation in DSM-IV disorders in metropolitan China.

Full Abstract

BACKGROUND:
This is the first study to examine variation across cohorts in lifetime risk of DSM-IV mental disorders in metropolitan China.

METHOD:
Face-to-face household interviews of 2633 adults in Beijing and 2568 adults in Shanghai were conducted from November 2001 to February 2002 using a multi-stage household probability sampling method. The Chinese World Mental Health (WMH) Survey Initiative version of the WHO Composite International Diagnostic Interview (WMH-CIDI) was used for assessment.

RESULTS:
Lifetime prevalence of any disorder was 13.2%. Alcohol abuse (4.7%), major depressive disorder (3.5%), and specific phobia (2.6%) were the most common disorders. The median age of onset was later for mood (43 years) than anxiety (17 years) and substance use (25 years) disorders. Compared to observed lifetime prevalence, the projected lifetime risk as of age 75 years increased by 106% for major depressive disorder (7.2%), and was uniformly higher for all disorders. Relative odds of any lifetime disorder were 4.7 in the most recent cohorts (ages 18-34) compared to the eldest cohorts (ages > or =65).

CONCLUSIONS:
The findings of this cross-sectional study tally with the view that rapid socioeconomic changes may bring about increasing incidence of mental disorders in China. However, prospective longitudinal studies are needed to confirm if the increase is real. Because of the huge size of the Chinese population, any increase in projected lifetime risk of mental disorders represents an enormous increase in the number of affected individuals.

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Author information

Author/s: Lee, Sing (S); Tsang, Adley (A); Zhang, Ming-Yuan (MY); Huang, Yue-Qin (YQ); He, Yan-Ling (YL); Liu, Zhao-Rui (ZR); Shen, Yu-Cun (YC); Kessler, Ronald C (RC);

Affiliation: Department of Psychiatry, The Chinese University of Hong Kong, HKSAR, PRC. singlee(-atsign-)cuhk.edu.hk

Grants: R01 DA016558 (Agency:NIDA NIH HHS) ; R01 DA016558-03 (Agency:NIDA NIH HHS) ; R01 MH069864-03 (Agency:NIMH NIH HHS) ; R01 MH070884-01A2 (Agency:NIMH NIH HHS) ; R01-MH069864 (Agency:NIMH NIH HHS) ; R13 MH066849-04 (Agency:NIMH NIH HHS) ; R13-MH066849 (Agency:NIMH NIH HHS)

Journal and publication information

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal: Psychological medicine (Psychol Med), published in England. (Language: eng)

Reference: 2007-Jan; vol 37 (issue 1) : pp 61-71

Dates: Created 2007/01/04; Completed 2007/11/13; Revised 2008/11/20;

PMID: 17038208, status: MEDLINE (last retrieval date: 12/26/2008)

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adolescent
Adult
Aged
China - epidemiology
Cohort Studies
Delivery of Health Care
Diagnostic and Statistical Manual of Mental Disorders
Female
Health Care Surveys
Health Services Needs and Demand

Health Services Needs and Demand
Humans
Individuality
Male
Mental Disorders - epidemiology; psychology; therapy
Middle Aged
Prevalence
Risk Factors
Time Factors
Urban Population

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