Correlations between neuropsychological test results and P300 latency during silent-count and button-press tasks in post-traumatic brain injury patients.

Full Abstract

To evaluate the correlations between memory function and intelligence and event-related potential, the P300 component for different tasks was studied for 30 post-traumatic brain injury patients (mean age 31.6 +/- 13.7 years; 23 male and 7 female). Memory function, intelligence, and depression were measured by using the Mini-Mental State Examination, the revised Wechsler Adult Intelligence Scale and the Self-Rating Depression Scale, respectively. P300 latency was measured during silent-count and button-press tests at three midline scalp (Fz, Cz, and Pz) sites for all subjects by using an auditory 'odd-ball' paradigm. Neuropsychological memory score was predicted by intelligence score, but neurophysiological P300 latency was predicted by memory score for the silent-count test and by intelligence score for the button-press test. These results show that the P300 event-related potential component is sensitive to the diverse nature of cognitive deficits in post-traumatic brain injury patients during different types of discrimination tasks. However, future research is necessary to replicate and extend these findings.

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Author information

Author/s: Reza, Faruque (F); Ikoma, Katsunori (K); Chuma, Takayo (T); Mano, Yukio (Y);

Affiliation: Department of Rehabilitation Medicine, Hokkaido University Graduate School of Medicine, N15 W7, Sapporo 060-8638, Japan.

Journal and publication information

Publication Type: Journal Article

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia (J Clin Neurosci), published in Scotland. (Language: eng)

Reference: 2006-Nov; vol 13 (issue 9) : pp 917-22

Dates: Created 2006/11/06; Completed 2007/01/09;

PMID: 17049245, status: MEDLINE (last retrieval date: 12/26/2008)

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adjustment Disorders - diagnosis; etiology; physiopathology
Adult
Brain Injuries - diagnosis; physiopathology; psychology
Cerebral Cortex - injuries; physiopathology
Cognition Disorders - etiology; physiopathology; psychology
Evoked Potentials - physiology
Humans

Intelligence - physiology
Intelligence Tests
Memory Disorders - etiology; physiopathology; psychology
Neuropsychological Tests
Predictive Value of Tests
Psychomotor Performance - physiology
Reaction Time - physiology

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