Enhancement of object representations in primate perirhinal cortex during a visual working-memory task.

Full Abstract

We compared single-cell activities in perirhinal cortex (PRh) as well as adjacent visual cortex (area TE) across two tasks. One task required the monkey to identify any stimulus repetition within a sequence of object stimuli. In the other task, the same stimuli were presented, but the monkey didn't have to remember them. PRh responses during the object-memory task were elevated relative to those during the second task. In TE, on the other hand, there were no significant task-related differences in responses. We did not observe task-related differences related to repetition effects in either brain area. The onset of the enhanced signal in PRh during the object-memory task occurred with a latency of 80 ms after the onset of the stimulus response, suggesting that it was the result of top-down feedback.

Author information

Author/s: Lehky, Sidney R (SR); Tanaka, Keiji (K);

Affiliation: Computational Neuroscience Lab, The Salk Institute, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA. sidney(-atsign-)salk.edu

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal: Journal of neurophysiology (J Neurophysiol), published in United States. (Language: eng)

Reference: 2007-Feb; vol 97 (issue 2) : pp 1298-310

Dates: Created 2007/02/09; Completed 2007/04/02;

PMID: 17108097, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

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