Research article summary (published 30 Aug 2006):

[Rapid identification of compounds in cortex moutan by liquid chromatography-tandem mass spectrometry]

Full Abstract

AIM: To analyze the chemical constituents of cortex moutan by liquid chromatography coupled with electrospray ionization mass spectrometry. METHODS: An on-line optimized HPLC-DAD/MS2 technique was employed. RESULTS: In the negative ion detection mode, 38 components such as monoterpene glucosides, galloylglucoses and acetophenones were isolated. Among them, over thirty compounds were identified, including paeonol, paeonilflorin, oxypaeoniflorin, benzoylpaeoniflorin, benzoyloxypaeoniflorin, galloylpaeoniflorin, galloyloxypaeoniflorin, mundanpioside A, C, D, E, H, etc. by the high performance liquid chromatography with diode-array detection in parallel with electrospray ionization and quadrupole-time of flight tandem mass spectrometry (HPLC-DAD/ESI-MS2). CONCLUSION: This method can be used to rapidly determine the constituents of cortex moutan.

Author information

Author/s: Xu, Shun-jun (SJ); Yang, Liu (L); Zhang, Mian (M); Wang, Zheng-tao (ZT);

Affiliation: Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210038, China.

Journal and publication information

Publication Type: English Abstract; Journal Article

Journal: Yao xue xue bao = Acta pharmaceutica Sinica (Yao Xue Xue Bao), published in China. (Language: chi)

Reference: 2006-Sep; vol 41 (issue 9) : pp 852-6

Dates: Created 2006/11/20; Completed 2008/02/11;

PMID: 17111832, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Acetophenones - analysis; chemistry; isolation & purification Chromatography, High Pressure Liquid - methods Drugs, Chinese Herbal - analysis; chemistry; isolation & purification Glucosides - analysis; chemistry; isolation & purification Molecular Structure Monoterpenes - analysis; chemistry; isolation & purification

Paeonia - chemistry Plant Extracts - analysis; chemistry; isolation & purification Plants, Medicinal - chemistry Reproducibility of Results Spectrometry, Mass, Electrospray Ionization - methods Tandem Mass Spectrometry - methods

Associated Chemicals: Acetophenones (0) ; Drugs, Chinese Herbal (0) ; Glucosides (0) ; Monoterpenes (0) ; Plant Extracts (0) ; moutan cortex (0) ; mudanpioside H (0) ; oxypaeoniflora (39011-91-1) ; paeonol (552-41-0)

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