Relapse prevention in schizophrenia: evidence from longterm, randomized, double-blind clinical trials.

Full Abstract

Fourteen long-term (duration at least 26 months) double-blind, randomized studies comparing second-generation antipsychotics (SGAs) with placebo, conventional antipsychotics, or two or more SGAs, published after 2002 have been reviewed and are summarized in this chapter. Methodological problems and factors influencing results such as patient populations involved, outcome criteria, and dosages of evaluated drugs are discussed.

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Author information

Author/s: Pecenak, Jan (J);

Affiliation: Department of Psychiatry, University Hospital Bratislava, Slovakia. jan.pecenak(-atsign-)faneba.sk

Journal and publication information

Publication Type: Journal Article; Review

Journal: Neuro endocrinology letters (Neuro Endocrinol Lett), published in Sweden. (Language: eng)

Reference: 2007-Feb; vol 28 Suppl 1 (issue ) : pp 49-70

Dates: Created 2007/07/12; Completed 2007/12/27;

PMID: 17262007, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Antipsychotic Agents - therapeutic use
Double-Blind Method
Humans
Placebos
Randomized Controlled Trials as Topic

Randomized Controlled Trials as Topic
Recurrence
Research Design
Schizophrenia - drug therapy; physiopathology
Treatment Outcome

Associated Chemicals: Antipsychotic Agents (0) ; Placebos (0)

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