Research article summary (published 27 Feb 2007):

The metabolic syndrome in polycystic ovary syndrome.

Full Abstract

Approximately one-third to one-half of all women and adolescent girls with polycystic ovary syndrome (PCOS) has the metabolic syndrome, associated with increased risk for cardiovascular disease and type 2 diabetes. Evidence suggests that insulin resistance is the likely link between PCOS and the metabolic syndrome. Early screening for impaired glucose tolerance, even in adolescents, is recommended. Lifestyle modification with increased physical activity and weight reduction remains first-line therapy. Insulin-sensitizing drugs may also ameliorate features of the metabolic syndrome in PCOS but long-term prospective studies are needed to determine the role of these drugs in the prevention of the metabolic syndrome.

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Author information

Author/s: Essah, Paulina A (PA); Wickham, Edmond P (EP); Nestler, John E (JE);

Affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia, USA. paessah(-atsign-)hsc.vcu.edu

Grants: K24HD40237 (Agency:NICHD NIH HHS)

Journal and publication information

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Review

Journal: Clinical obstetrics and gynecology (Clin Obstet Gynecol), published in United States. (Language: eng)

Reference: 2007-Mar; vol 50 (issue 1) : pp 205-25

Dates: Created 2007/02/16; Completed 2007/04/17; Revised 2007/12/03;

PMID: 17304037, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adolescent Adult Cardiovascular Diseases - complications Diabetes Mellitus, Type 2 Evidence-Based Medicine Female

Female Humans Metabolic Syndrome X - complications; therapy Polycystic Ovary Syndrome - complications; diagnosis Prevalence Risk Factors

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