Risk factors for dementia: data from the Conselice study of brain aging.

Full Abstract

Among the age-related diseases, the development of cognitive impairments, in particular dementia, is the most devastating for the individual and has great social and healthcare costs. Accurate information is needed about the prevalence and incidence of cognitive disorders and the physiology of the aging brain. In particular, only scarce data are available about the relationship between aging, cognitive status and nutritional factors. In order to address these issues, we planned the Conselice Study, a longitudinal study of physiological and pathological brain aging. The center involved in the study was the municipality of Conselice, (Province of Ravenna), in the Northern-Italian Region Emilia-Romagna. A total of 1,016 subjects aged 65 years and over was enrolled at baseline. Information about cognitive status at 4-years of follow-up was collected from 940 of them. These data have been used to estimate prevalence and incidence of dementia in the elderly Italian population and to investigate the possible role of homocysteine as a predictor of dementia.

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Author information

Author/s: Ravaglia, G (G); Forti, P (P); Maioli, F (F); Montesi, F (F); Rietti, E (E); Pisacane, N (N); Rolfo, E (E); Scali, C R (CR); Dalmonte, E (E);

Affiliation: Department of Internal Medicine, Cardioangiology, and Hepatology; University Hospital S. Orsola-Malpighi, Bologna, Italy. ravaglia(-atsign-)med.unibo.it <ravaglia(-atsign-)med.unibo.it>

Journal and publication information

Publication Type: Journal Article

Journal: Archives of gerontology and geriatrics (Arch Gerontol Geriatr), published in Netherlands. (Language: eng)

Reference: 2007-; vol 44 Suppl 1 (issue ) : pp 311-20

Dates: Created 2007/02/23; Completed 2007/05/18;

PMID: 17317467, status: MEDLINE (last retrieval date: 12/26/2008)

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Aged
Aging - physiology
Brain - physiopathology
Catchment Area (Health)
Cognition Disorders - epidemiology
Dementia - epidemiology; physiopathology
Follow-Up Studies

Humans
Hyperhomocysteinemia - epidemiology
Incidence
Italy
Prevalence
Risk Factors
Vitamin B Deficiency - epidemiology

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