Research article summary (published 27 Feb 2007):

Influence of music on the stress response in patients receiving mechanical ventilatory support: a pilot study.

Full Abstract

BACKGROUND: Music is considered an ideal therapy for reducing stress in patients receiving mechanical ventilation. Previous studies of the effect of music on stress in such patients have focused solely on indirect markers of the stress response rather than on serum biomarkers. OBJECTIVE: To explore the influence of music on serum biomarkers of the stress response in patients receiving ventilatory support. METHODS: A convenience sample of 10 patients receiving mechanical ventilation was recruited from an 11-bed medical intensive care unit. Patients were randomly assigned to listen to music or to rest quietly for 60 minutes. Levels of corticotropin, cortisol, epinephrine, and norepinephrine were measured 4 times during the 60 minutes. RESULTS: The levels of the 4 biomarkers of the stress response did not differ significantly between patients who listened to music and patients who rested quietly, though the levels of corticotropin and cortisol showed interesting trends. CONCLUSIONS: Additional research is needed with a larger sample size to evaluate further the influence of music on biochemical markers of the stress response in patients receiving mechanical ventilatory support. In future studies, confounding factors such as endotracheal suctioning and administration of medications that influence the stress response should be controlled for.

Author information

Author/s: Chlan, Linda L (LL); Engeland, William C (WC); Anthony, Anita (A); Guttormson, Jill (J);

Affiliation: University of Minnesota School of Nursing, Minneapolis, MN 55455, USA. chlan001(-atsign-)umn.edu

Journal and publication information

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal: American journal of critical care : an official publication, American Association of Critical-Care Nurses (Am J Crit Care), published in United States. (Language: eng)

Reference: 2007-Mar; vol 16 (issue 2) : pp 141-5

Dates: Created 2007/02/26; Completed 2007/05/03;

PMID: 17322014, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adrenocorticotropic Hormone - blood Aged Biological Markers - blood Epinephrine - blood Female Humans Hydrocortisone - blood Intensive Care Units

Intensive Care Units Male Middle Aged Music Therapy Norepinephrine - blood Pilot Projects Respiration, Artificial - psychology Stress, Psychological - blood; therapy

Associated Chemicals: Biological Markers (0) ; Hydrocortisone (50-23-7) ; Norepinephrine (51-41-2) ; Epinephrine (51-43-4) ; Adrenocorticotropic Hormone (9002-60-2)

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