A comparison of the mean signal change method and the voxel count method to evaluate the sensitivity of individual variability in visuospatial performance.

Full Abstract

This study compared the mean signal change method and the voxel count method in evaluating the sensitivity of individual variability in visuospatial performance using functional Magnetic Resonance Imaging (fMRI). Sixteen right-handed male college students (mean age 23.2 years) participated in this study as subjects. Functional brain images were scanned with a 3T MRI single-shot EPI method during a visuospatial task. No correlation was found between visuospatial performance and the number of activated voxels in the activated brain areas. Significant positive correlations, however, were found between visuospatial performance and the mean signal changes of activated voxels in the parietal, frontal and other areas. In conclusion, the mean signal change is more sensitive to individual variability in visuospatial performance than the number of activated voxels.

Author information

Author/s: Chung, Soon-Cheol (SC); Sohn, Jin-Hun (JH); Lee, Bongsoo (B); Tack, Gye-Rae (GR); Yi, Jeong-Han (JH); You, Ji-Hye (JH); Kwon, Ji-Hun (JH); Kim, Hyun-Jun (HJ); Lee, Soo-Yeol (SY);

Affiliation: Department of Biomedical Engineering, Research Institute of Biomedical Engineering, College of Biomedical & Health Science, Konkuk University, 322 Danwall-dong, Chungju, Chungbuk 380-701, South Korea. scchung(-atsign-)kku.ac.kr

Journal and publication information

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

Journal: Neuroscience letters (Neurosci Lett), published in Ireland. (Language: eng)

Reference: 2007-May; vol 418 (issue 2) : pp 138-42

Dates: Created 2007/04/30; Completed 2007/07/25;

PMID: 17379407, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

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