Research article summary (published 8 Apr 2007):

Physical activity and white matter lesion progression: assessment using MRI.

Full Abstract

We evaluated the association between physical activity and changes in white matter lesions (WMLs) on MRI in a sample of 179 older adults comprising 59 incident cases of Alzheimer disease, 60 persons with mild cognitive impairment, and 60 persons who remained cognitively stable over a median 5-year follow-up. Physical activity was not significantly associated with a decreased rate of periventricular or deep WML progression.

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Author information

Author/s: Podewils, L J (LJ); Guallar, E (E); Beauchamp, N (N); Lyketsos, C G (CG); Kuller, L H (LH); Scheltens, P (P);

Affiliation: Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. lpp8(-atsign-)cdc.gov

Grants: AG15928 (Agency:NIA NIH HHS) ; N01-HC 85086 (Agency:NHLBI NIH HHS) ; N01-HC-15103 (Agency:NHLBI NIH HHS) ; N01-HC-35129 (Agency:NHLBI NIH HHS) ; N01-HC-85079 (Agency:NHLBI NIH HHS)

Journal and publication information

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal: Neurology (Neurology), published in United States. (Language: eng)

Reference: 2007-Apr; vol 68 (issue 15) : pp 1223-6

Dates: Created 2007/04/10; Completed 2007/05/01; Revised 2007/12/03;

PMID: 17420407, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Activities of Daily Living Aged Alzheimer Disease - epidemiology; pathology Cognition Disorders - epidemiology; pathology Cohort Studies Demyelinating Diseases - epidemiology; pathology Disease Progression

Disease Progression Female Humans Magnetic Resonance Imaging - statistics & numerical data Male Motor Activity United States - epidemiology

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