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Research article summary (published 14 Aug 2007):

KIT-positive gastrointestinal stromal tumours in two Spanish ibex (Capra pyrenaica hispanica).

Full Abstract

Gastrointestinal mesenchymal tumours from two Spanish ibex (Capra pyrenaica hispanica) were examined grossly, histologically and immunohistochemically. One neoplasm was a 1.5 kg tan multinodular cavitated mass in the forestomach. The other tumour was a firm mural mass 1.2 cm in diameter in the colon. Microscopically, both tumours were formed mainly by spindle shaped cells arranged in closely packed interlacing fascicles. Neoplastic cells in both tumours labelled positively for KIT (CD117), vimentin and alpha-smooth muscle actin. These findings suggest that both neoplasms were gastrointestinal stromal tumours and most likely to be derived from the interstitial cells of Cajal or their progenitor cells.

 

Author information

Author/s: Velarde, Roser (R); Mentaberre, Gregorio (G); Sánchez, Joaquín (J); Marco, Ignasi (I); Lavín, Santiago (S);

Affiliation: Servei d'Ecopatologia de Fauna Salvatge, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain. Roser.Velarde(-atsign-)uab.es

Journal and publication information

Publication Type: Case Reports; Journal Article

Journal: Veterinary journal (London, England : 1997) (Vet J), published in England. (Language: eng)

Reference: 2008-Sep; vol 177 (issue 3) : pp 445-7

Dates: Created 2008/07/02; Completed 2008/09/09;

PMID: 17702621, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Associated Chemicals: Proto-Oncogene Proteins c-kit (EC 2.7.1.112)

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