Externalizing disorders in the offspring from the San Diego prospective study of alcoholism.

Full Abstract

OBJECT:
Conduct disorder (CD) and attention deficit hyperactivity disorder (ADHD) may be more prevalent in relatives of alcoholics and may predict alcohol and drug problems, but not all studies agree. This paper evaluates these questions in well-educated families of alcoholics and controls.

METHODS:
Data from 165, 14-25-year-old offspring in the San Diego Prospective Study were used to create Group 1 (n=17) with CD or ADHD and Group 2 (n=148) with no such diagnoses. Correlations and hierarchical logistic regressions evaluated characteristics associated with these disorders, comparing the impact of CD and ADHD.

RESULTS:
The rates of CD (6.1%) and of ADHD (4.8%) were not strikingly elevated, and did not relate to the family history of alcohol or drug use disorders. Group 1 offspring were more likely to have divorced parents, a relative with bipolar disorder, a higher intake of alcohol and illicit substances, and associated problems.

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Author information

Author/s: Schuckit, Marc A (MA); Smith, Tom L (TL); Pierson, Juliann (J); Trim, Ryan (R); Danko, George P (GP);

Affiliation: Department of Psychiatry (116A), University of California, San Diego and the VA San Diego Healthcare System, 3350 La Jolla, Village Drive, San Diego, CA 92161-2002, USA. mschuckit(-atsign-)ucsd.edu

Grants: AA05526 (Agency:United States NIAAA) ; R01 AA005526-22A2 (Agency:United States NIAAA) ; R01 AA005526-23 (Agency:United States NIAAA) ; R01 AA005526-24 (Agency:United States NIAAA) ; R01 AA005526-25 (Agency:United States NIAAA)

Journal and publication information

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal: Journal of psychiatric research (J Psychiatr Res), published in England. (Language: eng)

Reference: 2008-Jul; vol 42 (issue 8) : pp 644-52

Dates: Created 2008/04/25; Completed 2008/08/01;

PMID: 17765266, status: MEDLINE (last retrieval date: 11/6/2008)

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adolescent
Adolescent Behavior
Adult
Alcoholism - epidemiology
Attention Deficit Disorder with Hyperactivity - epidemiology
Bipolar Disorder - epidemiology; genetics
Child
Child Behavior Disorders - epidemiology
Child of Impaired Parents - psychology; statistics & numerical data
Comorbidity

Conduct Disorder - epidemiology
Control Groups
Divorce - statistics & numerical data
Family - psychology
Female
Humans
Male
Prevalence
Prospective Studies
Substance-Related Disorders - epidemiology

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