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| Research article summary (published 30 Aug 2007): |
Hypoglycemic and hypolipidemic effects of alcoholic extract of Tribulus alatus in streptozotocin-induced diabetic rats: a comparative study with T. terrestris (Caltrop).
Full Abstract
The extracts of both T. alatus and T. terrestris significantly decrease fasting glucose level in diabetic rats. After 4 and 6 hr, T. alatus extract showed significant reduction in glucose level as compared to T. terrestris. After 3 weeks of treatment with T. alatus extract, glucose level was significantly decreased to the normal level. Both the extracts also caused a significant decrease in the levels of glycosylated hemoglobin, total cholesterol, triglycerides and LDL-cholesterol. The percent of reduction in rats treated with T. alatus extract was significantly higher than that of the rats treated with T. terrestris. The results indicate that alcoholic extract of T. alatus possesses hypoglycemic activity in type-1 model of diabetes.
Author information
Author/s: El-Tantawy, W H (WH); Hassanin, L A (LA);
Affiliation: Drug Bioavailability Center, National Organization For Drug Control & Research, P O 29 Dokki, Cairo, Egypt. wldhmdy(-atsign-)yahoo.com
Journal and publication information
Publication Type: Comparative Study; Journal Article
Journal: Indian journal of experimental biology (Indian J Exp Biol), published in India. (Language: eng)
Reference: 2007-Sep; vol 45 (issue 9) : pp 785-90
Dates: Created 2007/10/02; Completed 2007/11/07;
PMID: 17907744, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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