Research article summary (published 30 Aug 1991):

New antimicrobial filicinic acid derivatives from Hypericum drummondii.

Full Abstract

Bioactivity-guided fractionation of the hexane extract of the stems and leaves of Hypericum drummondii has afforded four new filicinic acid derivatives: drummondin D, isodrummondin D, drummondin E, and drummondin F. The structures of these compounds were established by spectroscopic methods. All compounds possessed strong antibiotic activity against the Gram-positive bacteria Staphylococcus aureus and Bacillus subtilis and the acid fast bacterium Mycobacterium smegmatis.

Author information

Author/s: Jayasuriya, H (H); Clark, A M (AM); McChesney, J D (JD);

Affiliation: Department of Pharmacognosy, University of Mississippi, University 38677.

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal: Journal of natural products (J Nat Prod), published in UNITED STATES. (Language: eng)

Reference: -1991 Sep-Oct; vol 54 (issue 5) : pp 1314-20

Dates: Created 1992/04/21; Completed 1992/04/21; Revised 2006/11/15;

PMID: 1800634, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Acetophenones - chemistry; isolation & purification; pharmacology Anti-Bacterial Agents - chemistry; isolation & purification Benzopyrans - chemistry; isolation & purification; pharmacology Cyclohexanes - chemistry; isolation & purification; pharmacology

Magnetic Resonance Spectroscopy Microbial Sensitivity Tests Molecular Structure Plants - chemistry

Associated Chemicals: Acetophenones (0) ; Anti-Bacterial Agents (0) ; Benzopyrans (0) ; Cyclohexanes (0) ; drummondin F (122127-73-5) ; drummondin D (138169-52-5) ; isodrummondin D (138169-53-6) ; drummondin E (138169-54-7)

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