The neuropsychology of patients with clinically diagnosed idiopathic normal pressure hydrocephalus.

Full Abstract

OBJECTIVE:
To compare the neuropsychological performance of patients with idiopathic normal pressure hydrocephalus (INPH) with that of healthy individuals and to examine its relation to neurological signs, vascular comorbidity, and background factors.

METHODS:
A consecutive series of 58 patients with INPH underwent neurological, neuroradiological, and neuropsychological examinations. The neuropsychological tests, measuring vigilance, fine movements of the hands, learning, working memory, and aspects of executive functioning, were also administered to 108 healthy individuals.

RESULTS:
Patients performed worse than healthy individuals on all included tests. Significant correlations between test results were more frequent and stronger among patients and the degree of neuropsychological impairment was related to the severity of other signs of INPH. Patients with vascular risk factors performed worse than those without.

CONCLUSION:
The neuropsychological deficits in INPH are widely distributed, interrelated, associated with neurological signs, and aggravated by vascular comorbidity.

Learn Faster Today Improve your study skills

Author information

Author/s: Hellström, Per (P); Edsbagge, Mikael (M); Archer, Trevor (T); Tisell, Magnus (M); Tullberg, Mats (M); Wikkelsø, Carsten (C);

Affiliation: Institute of Neuroscience and Physiology, Göteborg University, Göteborg, Sweden. per.hellstrom@vgregion.se

Journal and publication information

Publication Type: Clinical Trial; Journal Article

Journal: Neurosurgery (Neurosurgery), published in United States. (Language: eng)

Reference: 2007-Dec; vol 61 (issue 6) : pp 1219-26; discussion 1227-8

Dates: Created 2007/12/28; Completed 2008/02/12;

PMID: 18162901, status: MEDLINE (last retrieval date: 11/6/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article (including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.

MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Aged
Aged, 80 and over
Female
Humans
Hydrocephalus, Normal Pressure - diagnosis; surgery
Male

Middle Aged
Neuropsychological Tests - statistics & numerical data
Neuropsychology - methods
Retrospective Studies
Statistics, Nonparametric
Treatment Outcome

These are the highest related articles currently in the database:

See 100+ related articles.