Role of echocardiography in the diagnosis and management of asymptomatic severe aortic stenosis.

Full Abstract

Calcification of normal tricuspid and congenital bicuspid valves is the most common cause of aortic stenosis in industrialized countries. There is compelling evidence that thickening and calcification in aortic valve disease is a complex inflammatory process and not simply age-related degeneration. Both aortic sclerosis and stenosis represent phenotypic expressions of one disease continuum. Patients with symptomatic severe aortic stenosis benefit from aortic valve replacement. However, management in the absence of symptoms remains challenging. While a delay of aortic valve replacement due to lack of symptom recognition may result in a dismal outcome, unselected premature aortic valve replacement may be associated with unbalanced risks of cardiac surgery. Echocardiography is the standard for evaluating the severity of aortic stenosis; however, most of the current echocardiographic parameters have limitations in predicting the onset of symptoms. This review summarizes the current guidelines and the emerging application of echocardiographic techniques in the management of asymptomatic severe aortic stenosis.

Author information

Author/s: Dal-Bianco, Jacob P (JP); Sengupta, Partho P (PP); Khandheria, Bijoy K (BK);

Affiliation: Division of Cardiovascular Diseases, Mayo Clinic Rochester, 200 First Street SW, Rochester, MN 55905, USA.

Journal and publication information

Publication Type: Journal Article; Review

Journal: Expert review of cardiovascular therapy (Expert Rev Cardiovasc Ther), published in England. (Language: eng)

Reference: 2008-Feb; vol 6 (issue 2) : pp 223-33

Dates: Created 2008/02/05; Completed 2008/03/05;

PMID: 18248276, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

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