Neuroanatomical correlates of motor acquisition and motor transfer.

Full Abstract

The acquisition of new motor skills is dependent on task practice. In the case of motor transfer, learning can be facilitated by prior practice of a similar skill. Although a multitude of studies have investigated the brain regions contributing to skill acquisition, the neural bases associated with the savings seen at transfer have yet to be determined. In the current study, we used functional MRI to examine how brain activation differs during acquisition and transfer of a visuomotor adaptation task. Two groups of participants adapted manual aiming movements to three different rotations of the feedback display in a sequential fashion, with a return to baseline display conditions between each rotation. Subjects showed a savings in the rate of adaptation when they had prior adaptive experiences (i.e., positive transfer of learning). This savings was associated with a reduction in activity of brain regions typically recruited early in the adaptation process, including the right inferior frontal gyrus, primary motor cortex, inferior temporal gyrus, and the cerebellum (medial HIII). Moreover, although these regions exhibit activation that is correlated across subjects with the rate of acquisition, the degree of savings at transfer was correlated with activity in the right cingulate gyrus, left superior parietal lobule, right inferior parietal lobule, left middle occipital gyrus, and bilaterally in the cerebellum (HV/VI). The cerebellar activation was in the regions surrounding the posterior superior fissure, which is thought to be the site of storage for acquired internal models. Thus we found that motor transfer is associated with brain activation that typically characterizes late learning and storage. Transfer seems to involve retrieval of a previously formed motor memory, allowing the learner to move more quickly through the early stage of learning.

Learn Faster Today Improve your study skills

Author information

Author/s: Seidler, R D (RD); Noll, D C (DC);

Affiliation: Division of Kinesiology, Department of Pshychology, University of Michigan, Ann Arbor, Michigan, USA. rseidler(-atsign-)umich.edu

Grants: AG-024106 (Agency:United States NIA) ; AG-20883 (Agency:United States NIA)

Journal and publication information

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal: Journal of neurophysiology (J Neurophysiol), published in United States. (Language: eng)

Reference: 2008-Apr; vol 99 (issue 4) : pp 1836-45

Dates: Created 2008/04/10; Completed 2008/06/17;

PMID: 18272874, status: MEDLINE (last retrieval date: 11/6/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article (including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.

MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adaptation, Physiological
Adult
Basal Ganglia - cytology; physiology
Biomechanics
Brain Mapping
Female
Humans
Image Processing, Computer-Assisted
Learning - physiology
Magnetic Resonance Imaging

Male
Memory - physiology
Motor Cortex - physiology
Motor Skills - physiology
Oxygen - blood
Parietal Lobe - physiology
Prefrontal Cortex - cytology; physiology
Psychomotor Performance - physiology
Rotation
Transfer (Psychology) - physiology

Associated Chemicals: Oxygen (7782-44-7)

These are the highest related articles currently in the database:

See 100+ related articles.