Research article summary (published 20 Oct 2007):

Improved separation efficiency of neurotransmitters on a native printed capillary electrophoresis microchip simply by manipulating electroosmotic flow.

Full Abstract

Separation and determination of dopamine and epinephrine with end-channel electrochemical (EC) detection integrated on a native printed microchip capillary electrophoresis (CE) system was investigated. Factors influencing the separation and detection were investigated and optimized. Results show manipulating EOF, which can be easily achieved by adjusting buffer pH, is a simple and effective way to achieve the baseline separation of dopamine and epinephrine in native polymeric microchips. Without surface modification of microchannel, printed microchips with advantages of low cost and easy preparation can achieve high performance like other microfluidic devices.

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Author information

Author/s: Yu, Hui (H); He, Feng-Yun (FY); Lu, Yu (Y); Hu, Yu-Lin (YL); Zhong, Hai-Yan (HY); Xia, Xing-Hua (XH);

Affiliation: Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal: Talanta (Talanta), published in England. (Language: eng)

Reference: 2008-Mar; vol 75 (issue 1) : pp 43-8

Dates: Created 2008/03/28; Completed 2008/07/16;

PMID: 18371845, status: PubMed-not-MEDLINE (last retrieval date: 11/6/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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