Capillary electrophoresis with laser-induced fluorescence: environmental applications.

Full Abstract

Capillary electrophoresis (CE), especially free-zone CE, offers a relatively simple separation with moderate selectivity based on the mobility of ions in solution. Laser-induced fluorescence (LIF) detection, an extremely sensitive technique, can be coupled with a variety of separation conditions to achieve sensitive and quantitative results. When these techniques are combined, CE/LIF provides the sensitivity and increased selectivity that makes trace level environmental analysis of fluorescent compounds possible at or below levels typical for gas chromatography (GC)/mass spectrometry (MS). We offer a panoramic review of the role of these tools in solving environmental and related analytical problems before providing a detailed experimental protocol.

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Author information

Author/s: Riddick, Lee (L); Brumley, William C (WC);

Affiliation: National Exposure Research Laboratory, Environmental Sciences Division, US Environmental Protection Agency, Office of Research and Development, Las Vegas, NV, USA.

Journal and publication information

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal: Methods in molecular biology (Clifton, N.J.) (Methods Mol Biol), published in United States. (Language: eng)

Reference: 2008-; vol 384 (issue ) : pp 119-34

Dates: Created 2008/04/08; Completed 2008/05/07;

PMID: 18392568, status: MEDLINE (last retrieval date: 11/6/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Electrophoresis, Capillary - methods
Environment
Environmental Monitoring - methods
Fluoresceins

Associated Chemicals: Fluoresceins (0)

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