 |
| Research article summary (published 21 Aug 2007): |
Anti-diabetic, anti-hyperlipidemic and spermatogenic effects of Amaranthus spinosus Linn. on streptozotocin-induced diabetic rats.
Full Abstract
Anti-diabetic, anti-hyperlipidemic and spermatogenic effects were studies with methanolic extract of stem of Amaranthus spinosus Linn (Family: Amaranthaceae) in diabetic rats. In streptozotocin (STZ)-induced diabetic rats, it was observed that both the standard drug (Glibenclamide) and methanolic extract of Amaranthus spinosus Linn. significantly exhibited control of blood glucose level on a 15 day model. Further, the methanolic extract also showed significant anti-hyperlipidemic and spermatogenic effects in STZ-induced diabetic rats. The methanolic extract has also accelerated the process of spermatogenesis by increasing the sperm count and accessory sex organ weights. The present investigation of the plant established some pharmacological evidence to support the folklore claim that it is used as an anti-diabetic.
Author information
Author/s: Sangameswaran, B (B); Jayakar, B (B);
Affiliation: Vinayaka Mission's College of Pharmacy, Vinayaka Missions University, Kondappanaickan patty, Salem, 636 008, Tamil Nadu, India. sangar1970(-atsign-)yahoo.co.in
Journal and publication information
Publication Type: Journal Article
Journal: Journal of natural medicines (J Nat Med), published in Japan. (Language: eng)
Reference: 2008-Jan; vol 62 (issue 1) : pp 79-82
Dates: Created 2008/04/11; Completed 2008/06/17; Revised 2009/10/30;
PMID: 18404348, status: MEDLINE (last retrieval date: 10/30/2009, IMS Date: 30 Oct 2009 00:00:00)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
External Links for this article
(including full text providers, if available):
Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.
This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.
MeSH headings (categories)
This article was linked to the MESH Headings shown below.
Related articles
These are the highest related articles currently in the database:
- Hypoglycemic and antihyperglycemic activity of Aegle marmelos seed extract in normal and diabetic rats.
5 May 2006 - Hypoglycemic and hypolipidemic effects of alcoholic extract of Tribulus alatus in streptozotocin-induced diabetic rats: a comparative study with T. terrestris (Caltrop). 30 Aug 2007
- Effect of ethanolic extract of Juglans regia L. on blood sugar in diabetes-induced rats. 30 Aug 2008
- Antidiabetic and antihyperlipemic effects of Clemeo felina. 30 May 2005
- Antihyperlipidemic effect of Eugenia jambolana seed kernel on streptozotocin-induced diabetes in rats. 30 Aug 2005
- The juice of fresh leaves of Catharanthus roseus Linn. reduces blood glucose in normal and alloxan diabetic rabbits.
31 Aug 2003 - Hypoglycemic and antihyperglycemic activity of Syzygium alternifolium (Wt.) Walp. seed extracts in normal and diabetic rats. 27 Feb 2001
- Glucose lowering efficacy of Ficus racemosa bark extract in normal and alloxan diabetic rats. 30 Aug 2002
- Effect of Cassia auriculata flowers on blood sugar levels, serum and tissue lipids in streptozotocin diabetic rats. 29 Nov 2002
- Effect of Phaseolus vulgaris on circulatory antioxidants and lipids in rats with streptozotocin-induced diabetes. 30 Dec 2001
Related Article Map
2/27/2001
8/30/2008
Higher Relevance Score (33)
Lower Relevance Score (22)
Legend: - FREE Full text Article. - Abstract only. 
- Title only. More help.
See a large map of 100+ related articles.