 |
| Research article summary (published 30 Mar 2009): |
Differential cerebellar and cortical involvement according to various attentional load: role of educational level.
Full Abstract
Recent imaging studies have evidenced various cerebral patterns dependent on educational level during cognitive tasks in neurodegenerative diseases. Determining relationships between educational status and cerebral activation during cognitive demands in physiological conditions may help to better understand the role of education on cognitive efficacy and functional reorganisation in pathological conditions. We proposed to analyse by functional MRI (fMRI) the relationship between educational status and cerebral activation during various attentional requests in healthy young adults. Twenty healthy young adults completed four successive conditions of a Go/No-go test of increasing complexity under fMRI. An effect of education was observed on attentional performances. Both in-scanner response times and cerebral activation increased during the Go/No-go paradigm. Healthy subjects with higher education exhibited higher activity in cerebellum and lower activity in medial prefrontal and inferior parietal regions compared with the healthy subjects with lower educational levels while performing the conditions of Go/No-go task. Our data evidence the influence of education on automatized strategies in healthy adults by modulating a functional balance of activation between cerebral cortex and cerebellar regions during attentional processes. 2008 Wiley-Liss, Inc.
Author information
Author/s: Bonnet, Melissa C (MC); Dilharreguy, Bixente (B); Allard, Michele (M); Deloire, Mathilde S A (MS); Petry, Klaus G (KG); Brochet, Bruno (B);
Affiliation: UMR-CNRS, University Victor Segalen Bordeaux, EPHE and Department of Neurology, CHU Bordeaux, France.
Journal and publication information
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal: Human brain mapping (Hum Brain Mapp), published in United States. (Language: eng)
Reference: 2009-Apr; vol 30 (issue 4) : pp 1133-43
Dates: Created 2009/03/16; Completed 2009/06/10;
PMID: 18465748, status: MEDLINE (last retrieval date: 6/10/2009, IMS Date: 10 Jun 2009 00:00:00)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
External Links for this article
(including full text providers, if available):
Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.
This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.
MeSH headings (categories)
This article was linked to the MESH Headings shown below.
Related articles
This article has not been indexed for related articles as yet, however you can still use the live related article search links below.
See a large map of 100+ related articles.