Simulation of physiology experiments--an alternative to animal use.

Full Abstract

Amphibian experiments on nerve-muscle preparation and heart are essential as per first year MBBS practical syllabus, for learning basic concepts in Physiology. Need was felt to design and develop computer based simulation software as an alternative to animal use, due to growing concern and stringent laws imposed by animal ethical bodies. Computer algorithms were developed for 13 amphibian experiments, by manually tracing the graphs obtained through mechanical experimentation and storing the X, Y coordinates for the end points of each line segment as data base tables. By retrieving the data base tables, one for each experiment, the computer simulated graphs were drawn using Visual Basic 6 with timer control and Macromedia Flash for animation effects. A CD-ROM consisting of the software for computer simulation of all the amphibian experiments, as an alternative to the conventional animal experiments, has been developed for the benefit of medical students across the country, as a useful active learning tool.

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Author information

Author/s: Nageswari, K Sri (KS); Devi, M Syamala (MS); Sharma, Rajeev (R);

Affiliation: Department of Physiology, Government Medical College, Chandigarh.

Journal and publication information

Publication Type: Journal Article

Journal: Indian journal of physiology and pharmacology (Indian J Physiol Pharmacol), published in India. (Language: eng)

Reference: -2007 Oct-Dec; vol 51 (issue 4) : pp 354-60

Dates: Created 2008/05/14; Completed 2008/06/05;

PMID: 18476389, status: MEDLINE (last retrieval date: 11/6/2008)

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Computer-Assisted Instruction
Education, Medical, Undergraduate - methods
Humans
Physiology - education
Teaching Materials

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