Subacute combined degeneration of the cord: Putnam-Dana syndrome.

Full Abstract

The association of anaemia and gastro-intestinal abnormalities with disorders of the brain, spinal cord, and peripheral nerves has been recognized since the mid 19th century. In early reports interpretable as subacute combined degeneration, anaemia was overlooked, and conversely in Addison's and other early reports of pernicious anaemia, cord and nerve changes were not recorded. This paper shows that Lichtheim first combined the two observations, and illustrates the excellent descriptions in 1890 of James Putnam and Charles Dana. The most complete early account was that of Russell, Batten and Collier in 1900. (c) 2008 S. Karger AG, Basel.

Author information

Author/s: Pearce, J M S (JM);

Affiliation: Department of Neurology, Hull Royal Infirmary, Hull, UK.

Journal and publication information

Publication Type: Historical Article; Journal Article

Journal: European neurology (Eur Neurol), published in Switzerland. (Language: eng)

Reference: 2008-; vol 60 (issue 1) : pp 53-6

Dates: Created 2008/06/04; Completed 2008/08/20;

PMID: 18520150, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

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