Research article summary (published 8 Jul 2008):

Noncholinergic neurons in the basal forebrain: often neglected but motivationally salient.

Full Abstract

Although noncholinergic neurons in the basal forebrain are known to contribute to cognition, their response properties in behaving animals is unclear. In this issue of Neuron, Lin and Nicolelis demonstrate that these neurons represent the motivational salience of sensory stimuli and may modulate cortical processing to direct top-down attention.

Learn Faster Today      Improve your study skills

Author information

Author/s: Lau, Brian (B); Salzman, C Daniel (CD);

Affiliation: Department of Neuroscience, Columbia University, 1051 Riverside Drive, Unit 87, New York, NY 10032, USA. brian.lau(-atsign-)columbia.edu

Journal and publication information

Publication Type: Comment; Journal Article

Journal: Neuron (Neuron), published in United States. (Language: eng)

Reference: 2008-Jul; vol 59 (issue 1) : pp 6-8

Dates: Created 2008/07/10; Completed 2008/08/12;

PMID: 18614024, status: MEDLINE (last retrieval date: 11/6/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

Comments and Corrections

CommentOn: Neuron. 2008 Jul 10;59(1):138-49. (PMID: 18614035)

External Links for this article (including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.

MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Action Potentials Animals Attention - physiology Motivation

Motivation Neurons - physiology Prosencephalon - cytology Rats

Related articles

These are the highest related articles currently in the database:

• Neuronal ensemble bursting in the basal forebrain encodes salience irrespective of valence. 8 Jul 2008
• Adenosine inhibits basal forebrain cholinergic and noncholinergic neurons in vitro. 18 Mar 2006
• Low voltage-activated calcium and fast tetrodotoxin-resistant sodium currents define subtypes of cholinergic and noncholinergic neurons in rat basal forebrain. 19 Jan 2005
• Fast modulation of prefrontal cortex activity by basal forebrain noncholinergic neuronal ensembles. 21 Aug 2006
• Effects of hypocretin-1 in 192-IgG-saporin-lesioned rats. 29 Sep 2006
• Chronic exposure to nerve growth factor increases acetylcholine and glutamate release from cholinergic neurons of the rat medial septum and diagonal band of Broca via mechanisms mediated by p75NTR. 4 Feb 2008
• Stereological estimates of the basal forebrain cell population in the rat, including neurons containing choline acetyltransferase, glutamic acid decarboxylase or phosphate-activated glutaminase and colocalizing vesicular glutamate transporters. Nov 2006
• [NADPH-diaphorase neurons and their interrelationship with microvascular vessels in the basal forebrain limbic structures and hypothalamus] 30 Dec 2006
• Differential co-expression of AMPA receptor subunits in substance P receptor-containing neurons of basal forebrain regions of C57/BL mice. 29 Mar 2006
• Synaptologic and fine structural features distinguishing a subset of basal forebrain cholinergic neurons embedded in the dense intrinsic fiber network of the caudal extended amygdala. 30 Aug 2006

See 100+ related articles.

Related Article Map

Legend: - FREE Full text Article. - Abstract only. - Title only. More help.

See a large map of 100+ related articles.