Research article summary (published 29 Sep 2008):

A rationalized set of default postulates that permit a coherent description of the immune system amenable to computer modeling.

Full Abstract

This discussion delineates and rationalizes a set of postulates that permit a coherent understanding of immune function. Although analytical tools such as mathematics and computer modeling have become very popular, simulation and data mining in the absence of a conceptual framework cannot increase understanding. The goal of this essay is to provide the foundation for a discussion that has as its goal the formulation of an agreed upon set of default postulates. Such a set is required to guide the algorithms needed to analyze complex immune behavior.

Learn Faster Today      Improve your study skills

Author information

Author/s: Cohn, M (M);

Affiliation: Conceptual Immunology Group, The Salk Institute for Biological Studies, La Jolla, CA, USA. cohn(-atsign-)salk.edu

Grants: RR07716 (Agency:United States NCRR)

Journal and publication information

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal: Scandinavian journal of immunology (Scand J Immunol), published in England. (Language: eng)

Reference: 2008-Oct; vol 68 (issue 4) : pp 371-80

Dates: Created 2008/09/10; Completed 2008/10/07;

PMID: 18782265, status: MEDLINE (last retrieval date: 11/6/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article (including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.

MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Algorithms Animals Computational Biology Computer Simulation

Computer Simulation Humans Immune System - physiology Models, Immunological

Related articles

These are the highest related articles currently in the database:

• Angular spectrum representation for the propagation of arbitrary coherent and partially coherent beams through atmospheric turbulence. 27 Feb 2007
• Synchronization in networks of networks: the onset of coherent collective behavior in systems of interacting populations of heterogeneous oscillators. 4 Mar 2008
• On the coherent description of diffusion-influenced fluorescence quenching experiments. 30 Dec 2006
• Cognitive ability experiment with photosensitive organic molecular thin films. 22 Jul 2006
• Extracting number-selective responses from coherent oscillations in a computer model. 29 Jun 2007
• A technological model to define access to electronic clinical records. 30 May 2005
• Coherent optical communication: towards realtime systems at 40 Gbit/s and beyond. 19 Jan 2008
• Risk factors for defaulting from tuberculosis treatment: a prospective cohort study of 301 cases in the Gambia. 29 Nov 2005
• Invasion percolation and critical transient in the Barabási model of human dynamics. 12 May 2007
• Precise control of molecular dynamics with a femtosecond frequency comb. 14 Mar 2007

See 100+ related articles.

Related Article Map

Legend: - FREE Full text Article. - Abstract only. - Title only. More help.

See a large map of 100+ related articles.