Research article summary (published 9 Sep 2008):

Phytotoxic polyacetylenes from roots of Russian knapweed (Acroptilon repens (L.) DC.).

Full Abstract

There are several factors thought to assist invasive weeds in colonization of ecosystems. One of these factors is allelopathy, the negative effect of chemicals produced by one plant on neighboring plants, frequently mediated through root exudates and other plant leachates. Acroptilon repens (Asteraceae) is one of the most invasive and ecologically threatening weed species in western North America. A bioassay-guided fractionation of the root extracts of this plant led to the isolation of five polyacetylenic compounds, of which one [5'-methoxy-1'-(5-prop-1-yn-1-yl-2-thienyl)-hexa-2',4'-diyin-6'-yl acetate] was hitherto unknown. The structures of these compounds were elucidated on the basis of spectroscopic analysis (IR, ESIMS, (1)H, (13)C NMR and 2D NMR). All of the compounds obtained, except 1-chloro-4-(5-penta-1,3-diyn-1-yl-2-thienyl)but-3-yn-2-ol, showed phytotoxic activity against Arabidopsis thaliana seedlings. The presence of 4'-chloro-1'-(5-penta-1,3-diyn-1-yl-2-thienyl)-but-2'-yn-3'-ol was detected in the root exudates of aeroponically grown A. repens plants. None of the polyacetylenes isolated in this study were found in Colorado soils collected between September 2006 and July 2007 in an A. repens colonized site. However, polyacetylene 5 in A. repens infested soil from Washington was found in June, 2007. Contrary to our previous report, the compound 7,8-benzoflavone (6) was not detected in root exudates, nor was it encountered in extracts of roots, aerial parts or infested soil. Since we could not repeat this work, the original report has been retracted [Stermitz, F.R., Bais, H.P., Foderaro, T.A., Vivanco, J.M., 2003. 7,8-Benzoflavone: a phytotoxin from root exudates of invasive Russian knapweed [A retraction]. Phytochemistry 64, 493-497.].

Author information

Author/s: Quintana, Naira (N); Weir, Tiffany L (TL); Du, Jiang (J); Broeckling, Corey D (CD); Rieder, Julie P (JP); Stermitz, Frank R (FR); Paschke, Mark W (MW); Vivanco, Jorge M (JM);

Affiliation: Department of Chemistry, Colorado State University, Fort Collins, CO 80523-1872, USA.

Journal and publication information

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal: Phytochemistry (Phytochemistry), published in United States. (Language: eng)

Reference: 2008-Oct; vol 69 (issue 14) : pp 2572-8

Dates: Created 2008/12/08; Completed 2009/01/16; Revised 2009/05/12;

PMID: 18789460, status: MEDLINE (last retrieved date: 5/12/2009)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

Comments and Corrections

ErratumIn: Phytochemistry. 2009 Feb;70(3):437.

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MeSH headings (categories)

This article was linked to the MeSH Headings (categories) shown below.

Arabidopsis - drug effects Asteraceae - chemistry Chromatography, High Pressure Liquid Molecular Structure North America

North America Plant Roots - chemistry Polyacetylenes - chemistry; isolation & purification; pharmacology Seedling - drug effects Soil - analysis

Note: Bold headings indicate primary MeSH headings or qualifiers.

Associated Chemicals: Soil (0) ; Polyacetylenes (25067-58-7)

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