Research article summary (published 30 Aug 2008):

Salivary free radical-scavenging activity is affected by physical and mental activities.

Full Abstract

OBJECTIVE AND DESIGN: Free radicals/reactive oxygen species (ROS) are related to inflammation, aging, and cancer. However, living systems have essential antioxidant mechanisms by which these harmful radicals can be scavenged, i.e., free radical-scavenging activity (FRSA). We measured the circadian rhythm of such activities by detecting salivary FRSA in healthy adults, and also examined how salivary FRSA is affected by physical and mental activities, which included (1) ingestion of beverage, (2) exercise, (3) comfortable/uncomfortable stimulation, and (4) smoking. METHODS: FRSA was determined by using the DPPH (1,1'-diphenyl-2-picrylhydrazyl) method. Statistical analysis for experimentally obtained median values was carried out using the Wilcoxon signed rank test. RESULTS: In circadian rhythm, FRSA was increased by food ingestion and relaxation. As to the individual activities, green tea and coffee ingestion increased FRSA, whereas swimming (P < 0.05) and dance lessons (P < 0.01) decreased it. Watching an amusing video program (P < 0.001) or stimulation by a pleasant aroma (P < 0.01) increased FRSA. In contrast, an unpleasant odor had no effect on FRSA. FRSA decreased immediately after smoking (P < 0.05), but increased thereafter (P < 0.01). CONCLUSION: Salivary FRSA was affected not only by physical activities, but also by mental activities. It may be a parameter for reflecting the health status of individuals.

Author information

Author/s: Atsumi, T (T); Tonosaki, K (K); Fujisawa, S (S);

Affiliation: Department of Human Development & Fostering, Meikai University School of Dentistry, Saitama, Japan.

Journal and publication information

Publication Type: Journal Article

Journal: Oral diseases (Oral Dis), published in Denmark. (Language: eng)

Reference: 2008-Sep; vol 14 (issue 6) : pp 490-6

Dates: Created 2008/10/01; Completed 2009/01/26; Revised 2009/04/07;

PMID: 18826379, status: MEDLINE (last retrieval date: 4/7/2009, IMS Date: 07 Apr 2009 00:00:00)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Activities of Daily Living Adolescent Adult Antioxidants - physiology Biphenyl Compounds - diagnostic use Child Child, Preschool Circadian Rhythm - physiology Coffee Dancing - physiology Drinking - physiology Eating - physiology Exercise - physiology Female Free Radical Scavengers - pharmacology Humans

Hydrazines - diagnostic use Laughter - physiology Lavandula Male Mental Processes Middle Aged Oils, Volatile Pentanoic Acids Plant Oils Relaxation - physiology Saliva - physiology Smell - physiology Smoking - physiopathology Swimming - physiology Tea Young Adult

Associated Chemicals: Antioxidants (0) ; Biphenyl Compounds (0) ; Coffee (0) ; Free Radical Scavengers (0) ; Hydrazines (0) ; Oils, Volatile (0) ; Pentanoic Acids (0) ; Plant Oils (0) ; Tea (0) ; 2,2-diphenyl-1-picrylhydrazyl (1898-66-4) ; isovaleric acid (503-74-2) ; lavender oil (8000-28-0)

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