Research article summary (published 25 Aug 2008):

Transfer of peanut allergy from the donor to a lung transplant recipient.

Full Abstract

Among solid organs, transfer of peanut allergy from donor to recipient has been implicated after liver transplantation. We report the first case in which such transfer occurred after a lung transplant. A 42-year-old woman with history of sarcoidosis underwent a successful bilateral lung transplant from a donor who died from anaphylactic shock after eating peanut-related food. Seven months later, she ate a peanut butter cookie at a transplant support group meeting. Immediately thereafter, she developed an anaphylactic reaction, but survived with prompt treatment. During subsequent follow-up, she could recall three prior episodes of wheezing and difficulty breathing after eating peanut-related foods. The first episode occurred 4 days after the transplant. Prior to her transplant, she never had problems eating peanuts. Skin-prick testing confirmed peanut sensitization. She avoided peanuts and, although her skin-prick test became negative, she still manifested peanut allergy when formally challenged orally with the food. She was advised to continue abstaining from all peanut-related foods. This case emphasizes the importance of considering donor allergy transfer when caring for all solid-organ transplant recipients in order to avoid a life-threatening event.

Author information

Author/s: Khalid, Imran (I); Zoratti, Edward (E); Stagner, Lisa (L); Betensley, Alan D (AD); Nemeh, Hasan (H); Allenspach, Lisa (L);

Affiliation: Department of Pulmonary and Critical Care Medicine, Henry Ford Health System, Detroit, Michigan 48202, USA. doc_ik(-atsign-)yahoo.com

Journal and publication information

Publication Type: Case Reports; Journal Article

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation (J Heart Lung Transplant), published in United States. (Language: eng)

Reference: 2008-Oct; vol 27 (issue 10) : pp 1162-4

Dates: Created 2008/10/17; Completed 2009/02/13;

PMID: 18926410, status: MEDLINE (last retrieved date: 2/18/2009)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MeSH Headings (categories) shown below.

Adult Anaphylaxis - mortality Child Fatal Outcome Female

Follow-Up Studies Humans Lung Transplantation - immunology Peanut Hypersensitivity - etiology Tissue Donors

Note: Bold headings indicate primary MeSH headings or qualifiers.

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