Zotepine-induced spontaneous ejaculation.

Full Abstract

A man with schizophrenia received regular haloperidol ester therapy, but his psychotic symptoms were not mitigated. A combination of zotepine and haloperidol was then used to relieve the psychotic symptoms. However, the patient developed spontaneous ejaculations, which occurred many times a day while undergoing haloperidol and zotepine therapy. These events were not preceded by sexual stimulation and were not associated with a pleasurable sensation. The discomfort disappeared after discontinuing zotepine. Zotepine-induced spontaneous ejaculation was, therefore, diagnosed. There are few reports of drug-related spontaneous ejaculation. Clinicians need to recognize the possibility of zotepine-related spontaneous ejaculation because sexual side effects have an impact on medical adherence.

Author information

Author/s: Wang, P-W (PW); Wang, S Y (SY); Huang, C-J (CJ);

Affiliation: Department of Psychiatry, Kaohsiung Kai-Suan Psychiatric Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

Journal and publication information

Publication Type: Case Reports; Journal Article

Journal: International journal of clinical pharmacology and therapeutics (Int J Clin Pharmacol Ther), published in Germany. (Language: eng)

Reference: 2008-Nov; vol 46 (issue 11) : pp 571-3

Dates: Created 2008/11/12; Completed 2009/01/15;

PMID: 19000555, status: MEDLINE (last retrieved date: 2/18/2009)

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